KP 103 (pharmaceutical)
(R,R)-2-(2,4-Difluorophenyl)-3-(4-methylenepiperidin-1-yl)-1-(1,2,4-triazol-1-yl)-2-butanol
CAS: 164650-44-6
Molecular Formula: C18H22F2N4O
KP 103 (pharmaceutical) - Names and Identifiers
KP 103 (pharmaceutical) - Physico-chemical Properties
| Molecular Formula | C18H22F2N4O |
| Molar Mass | 348.39 |
| Density | 1.26±0.1 g/cm3(Predicted) |
| Melting Point | 192-195°C |
| Boling Point | 512.2±60.0 °C(Predicted) |
| Solubility | 10 mM in DMSO |
| Appearance | powder |
| Color | white to beige |
| pKa | 12.11±0.29(Predicted) |
| Storage Condition | -20°C |
| In vivo study | Topical Efinaconazole solution (0.25 to 1%) is dose-dependently effective in treating both dermatophytoses, for 10 guinea pigs with interdigital tinea pedis or tinea corporis is investigated. The follow up study performs on day-30 and day-9 posttreatment demonstrated that the relapse rates for 1% Efinaconazole-treated animals with tinea pedis and for those with tinea corporis are 20 and 30%, respectively. When a single dose of 1% Efinaconazole is applied to the back skin 48 hours before fungal inoculation, 9 of the 10 animals are protected from the dermatophytosis, suggesting that active Efinaconazole is retained in skin tissue for at least 48 hours after dosing. |
KP 103 (pharmaceutical) - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.87 ml | 14.352 ml | 28.703 ml |
| 5 mM | 0.574 ml | 2.87 ml | 5.741 ml |
| 10 mM | 0.287 ml | 1.435 ml | 2.87 ml |
| 5 mM | 0.057 ml | 0.287 ml | 0.574 ml |
Last Update：2024-01-02 23:10:35
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Product Name: Efinaconazole Visit Supplier Webpage Request for quotationCAS: 164650-44-6
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Efinaconazole Visit Supplier Webpage Request for quotationCAS: 164650-44-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: Efinaconazole Visit Supplier Webpage Request for quotationCAS: 164650-44-6
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Efinaconazole Visit Supplier Webpage Request for quotationCAS: 164650-44-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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